Benzeneacetic acid, 3-bromo-α,α-difluoro-

Benzeneacetic acid, 3-bromo-α,α-difluoro- - Names and Identifiers

Name	2-(3-bromophenyl)-2,2-difluoroacetic acid
Synonyms	2-(3-bromophenyl)-2,2-difluoroacetic acid Benzeneacetic acid, 3-bromo-α,α-difluoro-
CAS	885068-76-8

Benzeneacetic acid, 3-bromo-α,α-difluoro- - Physico-chemical Properties

Molecular Formula	C8H5BrF2O2
Molar Mass	251.02
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD11167799

Benzeneacetic acid, 3-bromo-α,α-difluoro- - Introduction

2-(3-bromophene)-2,2-difluoroacetic acid(2-(3-bromophene)-2,2-difluoroacetic acid) is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: A solid powder.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethylformamide.
-Melting point: About 80-85 ℃.

Use:
- 2-(3-bromophenyl)-2,2-difluoroacetic acid can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
-It can also be used for research and development in the field of medicine.

Method:
- 2-(3-bromophenyl)-2,2-difluoroacetic acid can be prepared by the following methods: First, benzoic acid and triphenylphosphine are reacted in the presence of an activated carbon catalyst, 3-Bromophenylphosphine is obtained. Then, 3-bromophenylphosphine is subjected to hydrogenation of hydrofluoroboric acid to give 3-bromophenylboronic acid. Finally, 2-(3-bromophenyl)-2,2-difluoroacetic acid was obtained by acid treatment and deprotection reaction.

Safety Information:
- 2-(3-bromophenyl)-2,2-difluoroacetic acid should be stored in tightly sealed containers, away from heat and fire sources.
-Appropriate precautions, such as goggles and gloves, should be taken during handling or use to ensure adequate ventilation.
-Care should be taken to avoid inhalation, ingestion or skin contact to avoid irritation, allergies or other adverse effects.
-Before use, you should understand and comply with relevant safety procedures and regulations in detail. In case of accidental contact or ingestion, seek medical help immediately.

Last Update：2024-04-09 21:01:54